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Benefits Of Water-Soluble CBD Products | Nanop2 Water Soluble CBD liquid

Benefits Of Water-Soluble CBD Products

Benefits Of Water-Soluble CBD Products

If you have ever read about cannabidiol, then you will most likely have seen the term ‘CBD oil’ used everywhere. The term is now used interchangeably with CBD since CBD-rich extract that is derived from hemp is actually an oily substance. Also, additional oil carriers are used by many brands in popular products such as tinctures and capsules.

The important thing to understand is oil-based products do have inherent limitations that they carry with them. Oil-based products have bioavailability issues when used topically or ingested. The oil-based products do not absorb into the body effectively and a great deal of the product tends to get flushed unused out of the body.

Over the past several years, new technological advances have made what is referred to as water-soluble CBD possible. There are important features that new water-compatible products have that make them much more effective and also lower the cost per dose than traditional oil-carried offerings cost. Due to the effectiveness, an increasing number of companies have added the products to their lines- often completely replacing their oil-based offerings.

In this article, we are comparing water-soluble CBD oil and traditional CBD oil, and explore the term ‘water-soluble’ as well as what is occurring behind the scenes and review the technologies that are allowing these products to be produced.

Bioavailability Is What It’s All About
Oil and Water Separation

As discussed above, when material rich in CBD gets extracted from cannabis, it is in oil-based form. Like any other kind of oil, the substance, as well as its cannabinoid content in its hydrophobic meaning, doesn’t dissolve in water.

What bioavailability means is the amount of substance that enters into the bloodstream when it is introduced inside of the body and can have an active effect.

Given the fact that our bodies are comprised of around 60 percent water, naturally, CBD oil resists absorption in the bloodstream. That has a major impact on the bioavailability of many of the convenient and popular forms of taking CBD which include edibles, topicals, tinctures, and capsules.

For example, when oil-based CBD soft gels or capsules are swallowed, it is shown by some studies that as little as 4% of the substance makes it to the bloodstream. That means as much as 96% of CBD gets flushed out of the body without it having an active effect ever. Its incompatibility with water also means the small percentage that does actually have an effect on a user will have a delayed onset.

The delayed onset and low bioavailability levels have forced the cannabis industry to come up with a solution.

Although serious, those issues don’t plague all CBD ingestion forms. For instance, for vaping the natural oil form is what works well. That is due to the fact that CBD, as well as other cannabis molecules, get carried by small vapor particles when they are atomized. Those particles are absorbed easily by the lungs when they are inhaled.

What is Water Soluble CBD Oil?

Water-soluble is a term that is not actually totally accurate, as many people will be quick to say. Over the past several years, a number of new technologies have allowed CBD producers to make products that break apart the oil particles into small molecules. Those particles then are emulsified, which allows them to stay stable within this specific form.

Emulsified CBD-rich oils, despite the name, don’t dissolve in water actually. They instead get transformed into a form that is more water-friendly. ‘Water-compatible’ is a term that is more accurate for those products. The small size of the particles enables them to disperse in the water – which increases the compounds surface area effectively.

Despite that fact, ‘water-soluble’ is a term that has become established within the CBD industry because of its widespread use in marketing CBD products. The ‘water-friendly’ products that result are both powder and liquid forms and are most frequently used to produce drinks, edibles, topicals, capsules, and tinctures.

Side Note: Many people mistakenly believe CBD isolate is actually water soluble. However, that is not the case. The actual CBD molecule is hydrophobic which means it won’t mix with water, even when it is in isolated crystalline form.

Forms of Water Soluble CBD

In order to create those products, CBD in oil form, as well as other cannabis molecules, get broken into small particles and emulsified or transported by a hydrophilic (water-friendly) carrier. Those forms require using a surfactant and reduce the amount of surface tension between the liquid and oil.

There are several different methods for manufacturing water-friendly CBD product that vary in terms of their effectiveness. Let’s take a close look at the most common methods that are currently being used in the industry.


Nanoemulsions are the best method today to create water-soluble CBD oil. Those products are made by braking cannabis extract up into 10-100 nanometer droplets.

A low surfactants amount is required by the mechanical process that is used for creating nanoparticles. Also, the method allows for the use of all natural surfactants. The benefits reduce the disadvantages that are associated with high-surfactant and synthetic use. Those particles are also translucent that means they may be added into drinks without them being detected visually.

Our product line at Big Sky Botanicals features many options that use the superior knowledge that allows for 50% and higher bioavailability for such products as tinctures and capsules – which is five times more potent than oil-based products.


Microemulsions are 100 to 5000 nanometer droplets that are formed by solubilizing CBD oil within water. The emulsions are made through the use of a chemical process have the drawback of needing to high surfactant amounts which can result in the user having some negative side effects. The size emulsion isn’t found within the CBD very commonly.


Liposomes are spherical structures that contain water and range in size from 50 up to 5000 nanometers. These are made out of a water-friendly (hydrophilic) internal compartment with a water-insoluble (hydrophobic) bilayer surrounding it. CBD extract may be stored within the bilayer membrane.

Within the hemp industry products that use the technology are common. The downside to the methods is that very complex manufacturing procedures are used and high surfactant levels are required.

Water Soluble CBD Benefits

There are a number of benefits that water-soluble capsules and tinctures have when compared with traditional oil-based products:

Less Waste, More Effective

Higher bioavailability means less of the product gets wasted when it is ingested and more of the product is put to use actively.

Quicker Onset

This type of product absorbs more rapidly in the body and also become active more quickly compared to oil-based products.

Versatile Use

Due to developments in technology, emulsions are making it possible for cannabis molecules can be mixed in water-based beverages and drink and other applications as well.

Better Value

Depending on which method is used for creating the water-soluble product, its bioavailability may increase up to 500%. In that case, you only need 1/5th of the dosage to get the same results. The creates less waste and frequently lowers the price per dose when it is compared to oil-based similar products.